Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
نویسندگان
چکیده
Murine lymphoma L5178Y cells in culture were exposed to 5 fj.M 6-azauridine (6-aza-UR) for up to 8 hr. The nucleotides in the acid-soluble extracts were determined by highpressure liquid chromatography. The concentrations of uracil and cytosine nucleotides decreased rapidly in the treated cells. Adenosine 5'-triphosphate and adenosine 5'diphosphate increased steadily, whereas guanosine 5'-di-
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عنوان ژورنال:
- Cancer research
دوره 37 12 شماره
صفحات -
تاریخ انتشار 1977